S4 is another Selective Androgen Receptor Modulator (SARM) that is able of exerting supra-physiological amounts of anabolic activity in the body with no negative androgenic side effects.
What Exactly Is S4 (Andarine)?
S4 is a SARM taken orally (no injections needed) that can result in substantial increases of strength, lean muscle mass, and fat loss.
It is non-steroidal and has tissue-selective anabolic effects in muscle and bone, while sparing other androgenic effects that come from anabolic androgenic steroids (AAS).
S4 also greatly improves your ability to burn fat.
It doesn’t bloat as it doesn’t convert to estrogen or progesterone, and the size it produces is very dry.
Basically, it is the ultimate cosmetic SARM. When I say that, I mean that each pound that S4 packs on you will be lean, bloat free weight, it will help rip you up, and it helps carve a lot more detail into the muscle.
If you are familiar with Steroids that are DHT derivatives in particular, you are probably well aware of how they are the absolute best drugs on the planet for making you look even more like a granite statue once you are already lean.
There’s a reason bodybuilders load their body with DHT drugs pre-contest before a show, because it drys them out, brings out a lot more detail in the muscle, and gives a drastic hardening effect to their physique.
DHT derivatives are unfortunately extremely notorious for causing bad Androgenic side effects, especially male pattern baldness.
This Is Where S4 Shines!
S4 is very alike to DHT derivative steroids in the sense that it provides the same benefits you would experience from drugs like Masteron or Winstrol, WITHOUT subjecting yourself to the ruthless Androgenic side effects.
That means zero chance of hair loss, zero chance of acne, zero chance of body hair growth, zero chance of virilization in women, etc.
S4 Is Basically The SARM Version Of Masteron
Just Some Of S4’s Incredible Attributes:
- Great lean mass builder
- Notable increases in strength and endurance
- Enhanced levels of fat oxidization
- Can completely off-set catabolism in a calorie deficit
- Body fat melts off so much easier
- Greater levels of muscle hardness, dryness, and vascularity
One thing that is important to note is that all SARMs don’t work the same, despite exerting anabolic activity in the same manner.
Each SARM has a different way it affects the body, as they each have their own gene transcription effects.
Consequently, results from a SARM like S4 could be vastly different than that of Ostarine or LGD-4033 for example. And it definitely is a lot different results wise.
S4 is not as potent of a mass builder as LGD-4033, or even Ostarine for that matter, but it truly can help transform a physique nonetheless, and combined with other SARMs which potentiate its’ effects, S4 makes for an absolutely game changing SARM from a cosmetic standpoint.
Dosing, Side Effects, and PCT
While some fat loss and body recomposition is evident from a 25mg low daily dose, real results will start to become apparent at the 50 mg + range per day.
The most commonly utilized dose in several studies, and is widely known as the “recommended dose” in anecdotal logs made by researchers is 50-100 mg per day as it provides the maximum benefit with the least side effects.
This range doesn’t have a definitive set recommended dose because some individuals are more prone to the one negative side effect of S4 at higher end doses (50+ mg).
This side effect is the eyesight side effect.
S4 has one particularly unique and odd side effect that no other SARM does.
S4 has a tendency to bind to the ocular receptors in the eyes, which can cause a temporary yellow tint to be noticed in sight, and some issues adjusting from dark to light settings.
This is most notable during the night time.
While this may seem scary as shit, it is only temporary and can be completely avoided by simply tapering your dose back a bit until the side effect disappears, or just discontinuing your S4 research, which will also stop this side effect from causing you discomfort.
The tricky thing with S4 research is basically finding the max dose you can get away with without getting vision side effects, as low doses of S4 don’t provide much in the size department.
But once your research starts to get closer to 70-80mg per day (if you can get that high), with 100 being the max ideal dose (if you can handle it), then very substantial and noticeable increases in lean muscle mass have been noted.
The half-life of S4 is very short, so splitting your daily research into at least 2 doses is recommended. One in the morning, and one at night.
Typically, it is recommended that your research starts at an assessment dose of 25mg per day, and only taper up SLOWLY.
Basically, you don’t want to bump the dose too high too fast or else you could very well thrust yourself into side-effect city.
50mg+ is where the vision side effect can become common in certain individuals, so approach your tapering process with caution.
After seeing how your research subject responds to 25mg per day for a week or two, you can bump it up to the 50mg threshold dose and assess if any side effects occur.
There will be likely none, but this is where you want to start titrating the dose EXTREMELY slow.
Stay at 50mg for at least a week or two. If your research is vision impairment free, then you can bump it 10mg to 60mg total per day.
Do this for another week or two minimum. After this, then you can bump it another 10mg.
Rinsing and repeating this process is recommended until you reach a dose where side effects are noted and you can taper it back a tad to a manageable side effect free dose, or you reach the max out dose of 100mg where diminished returns will make it useless to even attempt to make it any higher than this dose.
As far as cycle duration goes, S4 benefits will be noted throughout the course of an entire cycle extending for several months.
The slow tapering process necessary to avoid side effects makes S4 ideal for cycles extending to around 12 weeks.
You may encounter some slight testosterone suppression after the 4-week mark, so it is recommended you keep ELIMINATE on hand and use a pill of it alongside your SARMs each day to offset unwanted suppression symptoms.
You will also need the K1NGS BLOOD for after your cycle of research is complete to use at 3 pills per day for 4 weeks to bring your testosterone and estrogen levels back to homeostasis in as quick a period of time as possible to preserve lean mass and strength gains.
S4 Vs. All Other SARMs
Although the mechanism by which S4 exerts anabolic activity at the androgen receptor is the same as other SARMs, it has its’ own unique gene transcription effects.
How S4 differs from other SARMs in particular results wise is the sheer cosmetic look it gives that no other compound can replicate.
The hardness, dryness and vascularity that S4 can bring to the muscle is unmatched, and its recomposition effects at a high enough dose can be staggering.
S4 isn’t as much of a mass builder as it is a muscle polisher so to speak.
This mainly how it differs from the traditional popular SARMs like Ostarine and LGD-4033, which are primarily known for their ability to pack on size.
In a lean physique, S4 will carve out amazing details and bring an aesthetic look to the physique that would otherwise be impossible to achieve (much like DHT drugs).
Ultimate Body Transformation Stack Including S4
A sample of a very productive S4 cycle is as follows:
Week 1-12: Ostarine/MK-2866 25mg per day dosed once per day in the AM
Week 1-12: Cardarine/GW-510516 20mg per day dosed all at once 20 minutes pre-workout or before physical activity (if not doing physical activity that day have it in the AM)
Week 1-12: S4 50mg per day split into 2 doses per day…. 25mg in the AM and 25mg in the PM
Week 1-12: 3 Pills EL1MINATE dosed three times per day.
(Mini-PCT) Week 13-16: 5 Pills K1NGS BLOOD dosed twice per day.