Accadine (AC-262536) is a compound which acts as a selective androgen receptor modulator. Chemically it possesses endo-exo isomerism, with the endo form being the active form. It acts as a partial agonist for the androgen receptor with a Ki of 5nM, and no significant affinity for any other receptors tested.
AC-262 isn’t one of the stronger SARMs in the spectrum, at a mere 2/3 the anabolic potency of testosterone, but it’s rare and as a result is still potentially undetectable in traditional PED tests, drug-tested athletes would potentially get a sizeable edge from this compound.
Although studies are limited, there are 4 core benefits of supplementing with AC-262,536.
- AC-262,536 may increase muscle mass
A 2-week study of male castrated rates indicated that AC-262,536 significantly improved anabolic parameters, particularly in stimulating growth in the levator ani (pelvic muscle). 
In comparison to testosterone, AC-262,536 improved muscle growth at 66% the capacity of testosterone, but without the negative side effects of steroid use.
- AC-262,536 may help Alzheimer’s Disease
Reduced Androgen Receptor levels are a known symptom of Alzheimer’s Disease. A study by Acadia Pharmaceuticals shows that AC-262,536 restored AR levels in castrated mice to intact levels. 
Additionally, the study showed that mice treated with AC-262,536 showed greater spatial memory than control rats, suggesting that the SARM may help reduce Alzheimer’s symptoms.
More research is needed, but the results are promising.
- AC-262,536 may help prevent prostate cancer
AC-262,536 shows promise in the prevention of prostate cancer thanks to its ability to strongly antagonize the effect of dihydroxytestosterone (DHT). The link between DHT and prostate cancer is DHT’s ability to increase the growth of the prostate cells.
As AC-262,536 decreases the effects of DHT, it shows promise in minimising the risk of prostate cancer as well as decreasing the size of the prostate overall.
- AC-262,536 decreases elevated levels of Luteinizing Hormone
Studies show that AC-262,536 decreases elevated levels of Luteinizing Hormone (LH). Although this may seem counter-intuitive as LH is a precursor to natural testosterone production, there are some diseases that may benefit from lowering abnormally high LH levels.
Keep in mind that even with decreased LH levels, AC-262,536 still managed to produce similar effects of testosterone on muscle growth and development.
As with most SARMs, studies show that AC-262,536 does not appear to have any side effects common to steroidal compounds. Unlike testosterone, AC-262,536 does not cause prostate enlargement or testes shrinkage – in fact, it has been shown to suggest a decrease in prostate size.
However, as it is still in early developmental stages, this does not mean that there are no long-term effects. More research needs to be conducted on this compound.
As there have not been any human clinical studies to date, dosing recommendations come from individuals who have used AC-262,536 for performance and strength enhancing purposes.
10mg-30mg per day
Post Cycle Therapy (PCT)
Post Cycle Therapy (PCT) is required when taking SARMS to help preserve muscle gains, prevent fat accumulation, maintain mood and motivation, and retain strength in muscles. Cycling also helps to allow hormone levels to return to their natural state in order to prevent unwanted dependency.
Typically, a PCT will last the same duration as supplementation. So if a user supplemented with a hormone for 12 weeks, a PCT of 12 weeks would also be required to bring their hormones back to baseline.
But do I need a PCT when taking SARMs?
Because SARMs do not disrupt hormone levels in the body, a traditional PCT is not necessary. However, many users report taking a mini PCT such as ARIM-Rx for 4 weeks to ensure hormone levels are balanced.